Translational Research in Pain and Itch

Master Pain and Itch Science: Translating Mechanisms into Therapeutic Innovation

Explore this authoritative volume presenting cutting-edge advances in the biology and clinical translation of pain and itch. Far beyond descriptive models, this second edition integrates mechanistic insight with practical treatment strategies rooted in translational research.

Key Features:

Mechanistic Insight Meets Clinical Relevance: Detailed exploration of sensory mechanisms behind pain and pruritus—from peripheral nociceptors to central sensitization—linked directly to emerging therapies and clinical paradigms.

Updated and Expanded Coverage: Includes five fully revised chapters reflecting recent discoveries and five brand-new chapters addressing the latest developments in pain and itch research, offering the most current perspectives available.

Model Systems to Human Translation: Features protocols for assessing pain and itch in animal models and human subjects, highlighting translational approaches that bridge basic research with clinical application.

Immune and Glial Interactions: Examines the contributions of microglia, astrocytes, T-cell subsets, and inflammatory mediators, revealing new targets and strategies for immune-based pain modulation.

Therapeutic and Multidisciplinary Strategies: Profiles next-generation treatment modalities targeting novel receptors, neuroimmune pathways, neuromodulatory techniques, and team-based chronic pain management frameworks.

Perfect for neuroscientists, neurologists, anesthesiologists, pharmacists, and translational researchers, this volume provides the scientific depth and clinical context essential for advancing pain and itch care. Whether you’re developing new interventions, designing translational studies, or refining patient protocols, this book equips you with the latest evidence and tools to drive meaningful outcomes.