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The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

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ISBN

978-0124171466

Authors

Joerg Bluemel (Editor), Sven Korte (Editor), Emanuel Schenck (Editor), Gerhard Weinbauer (Editor)

Edition Number

1st

Copyright Year

March 13, 2015

File Size

30.1 MB

Publisher

Academic Press

Pages

653

Nonhuman Primate Drug Development

A specialized reference on the use of nonhuman primates in pharmaceutical drug development, nonclinical safety assessment, and toxicology. It covers study design, species selection, regulatory toxicity testing, comparative physiology, pathology, immunotoxicology, reproductive biology, animal welfare, and the assessment of biologics and small-molecule drugs.

Key Features

  • Covers nonhuman primate models in drug development
  • Explains nonclinical safety and regulatory toxicity testing
  • Discusses species selection and study design
  • Covers toxicologic pathology and comparative physiology
  • Addresses biologics and small-molecule safety assessment
  • Includes immunotoxicology and reproductive biology
  • Discusses genetic polymorphisms and interspecies differences
  • Covers animal welfare legislation and the 3Rs
  • Includes practical experimental techniques and methodologies
  • Useful for toxicologists, toxicologic pathologists, pharmaceutical scientists, and researchers
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