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Pathology of Genetically Engineered and Other Mutant Mice

Pathology of Genetically Engineered and Other Mutant Mice

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ISBN

978-1119624592

Authors

John P. Sundberg (Editor), Peter Vogel (Editor), Jerrold M. Ward (Editor)

Edition Number

1st

Copyright Year

‎ October 27, 2021

File Size

170.2 MB

Publisher

Wiley-Blackwell

Pages

555

Pathology of Genetically Engineered and Mutant Mice

This updated reference provides a comprehensive guide to identifying and interpreting pathological changes in genetically engineered, mutant, and wild-type mice. Organized by organ system, it combines diagnostic guidance with hundreds of color photographs illustrating common and uncommon lesions. Covering mouse pathology, genetic nomenclature, necropsy techniques, and animal model validation, it supports accurate pathological assessment in biomedical research and veterinary practice.

Key Features

  • Provides comprehensive coverage of pathology in genetically engineered and mutant mice
  • Examines pathological findings across all major organ systems
  • Includes hundreds of color photographs illustrating common and rare lesions
  • Introduces mouse pathology and genetic nomenclature
  • Explores databases and resources for analysing mutant mouse models
  • Discusses the validation and interpretation of genetically modified animal models
  • Explains practical necropsy methods and tissue examination techniques
  • Covers lesion identification, classification, and grading for computational analysis
  • Provides diagnostic approaches to respiratory, gastrointestinal, cardiovascular, skeletal, and other systems
  • Serves as a reference for veterinary and medical pathologists, toxicologists, and biomedical researchers
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