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Oral Lichen Planus and Lichenoid Lesions

Oral Lichen Planus and Lichenoid Lesions

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ISBN

9783031297656

Authors

Gaetano Isola, Simona Santonocito, Rosalia Leonardi, Alessandro Polizzi

Edition Number

1

Copyright Year

2023

This comprehensive, evidence-based monograph offers an in-depth exploration of Oral Lichen Planus (OLP), one of the most frequent oral potentially malignant disorders (OPMDs). The book provides a meticulous examination of the disorder, from its complex and still partly unknown pathogenesis to its clinical presentation, differential diagnosis, histopathological aspects, and current therapeutic strategies.

Special attention is given to the epidemiology and etiological theories, including immune-mediated mechanisms, genetic predispositions, and environmental factors. The text also explores the clinical and histological overlap between OLP and other oral mucosal conditions, equipping clinicians with practical tools to achieve accurate diagnoses.

By integrating the most recent scientific evidence with expert clinical insight, this volume becomes a valuable reference for clinicians managing challenging oral lesions and researchers seeking to advance understanding of this enigmatic disease. It highlights both the current limits of knowledge and the opportunities for future research, aiming to guide toward standardized diagnostic criteria and more effective therapeutic options.


Key Features:

  • Comprehensive Review: Covers all aspects of Oral Lichen Planus, including epidemiology, etiopathogenesis, clinical features, diagnosis, management, and prognosis.
  • Differential Diagnosis: Provides clear guidance on distinguishing OLP from other clinically and histologically similar oral conditions, such as leukoplakia, lupus erythematosus, and lichenoid reactions.
  • Evidence-Based Approach: Synthesizes the latest research findings and clinical guidelines, offering up-to-date and scientifically grounded recommendations.
  • Focus on Pathogenesis: Explores the complex immune and molecular mechanisms believed to contribute to OLP, with discussions on controversial and emerging theories.
  • Therapeutic Strategies: Evaluates both conventional and emerging therapies, including corticosteroids, immunomodulators, and phototherapy, with an emphasis on individualized treatment plans.
  • Research-Oriented Perspective: Identifies key gaps in knowledge and suggests directions for future investigations, particularly in developing universally accepted diagnostic criteria.
  •  Clinical Relevance: Tailored to the needs of oral medicine specialists, dentists, dermatologists, and general clinicians dealing with ambiguous oral lesions.
  • Educational Utility: A valuable resource for postgraduate students, residents, and researchers in dentistry, pathology, and oral medicine.
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