Mouse Genetics Methods and Protocols

Mouse Genetics: Methods and Protocols

Edited by Shree Ram Singh and Vincenzo Coppola, this volume presents practical laboratory methods for studying mouse genetics and modeling human diseases. It focuses on generating transgenic mice, manipulating genes of interest, tracing cell lineages, and investigating disease mechanisms. Each chapter provides an introduction, required materials, step-by-step protocols, and troubleshooting notes to support reproducible research.

Key Features:

• Covers essential techniques in mouse genetics and molecular biology
• Explains methods for generating transgenic mouse models
• Describes approaches for manipulating genes of interest
• Presents techniques for tracing cell lineages
• Explores mouse models used to investigate human diseases
• Provides step-by-step, laboratory-based protocols
• Lists materials and equipment required for each method
• Includes troubleshooting notes and practical recommendations
• Supports reproducibility in genetic and biomedical experiments
• Designed for geneticists, molecular biologists, students, and research fellows