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Molecular Epidemiology Principles and Practices

Molecular Epidemiology Principles and Practices

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ISBN

9780080925660

Authors

: Paul A. Schulte, Frederica P. Perera

Edition Number

1

Copyright Year

1998

Now available in paperback, this groundbreaking volume has been instrumental in defining and advancing the field of molecular epidemiology, bridging the gap between molecular biology and population-level health research. Designed for both epidemiologists and molecular biologists, the book serves as a foundational resource for understanding how genetic and molecular data can be integrated into traditional epidemiologic models to uncover the determinants of human disease.

Molecular Epidemiology provides a thorough explanation of how biological markers (biomarkers) are used to measure exposure, susceptibility, and disease progression, and how these markers enhance the accuracy and precision of epidemiological investigations. The book clearly illustrates that while molecular epidemiology retains the essential framework of classical epidemiology, it brings powerful new tools to the study of etiology, risk assessment, and prevention strategies.

Widely regarded as essential reading for professionals and students in public health, epidemiology, toxicology, and molecular biology, this text is a landmark resource in the evolution of interdisciplinary research aimed at understanding and controlling disease at the molecular level.


Key Features:

  •  Bridges Two Disciplines: Integrates molecular biology techniques with epidemiologic study design, creating a new framework for disease investigation.

  •  Focus on Biomarkers: Explores the use of biological markers to measure environmental exposure, genetic susceptibility, and disease status, enhancing the precision of epidemiologic data.

  •  Accessible to Diverse Audiences: Written for epidemiologists unfamiliar with molecular biology and biologists new to population health studies, with clear explanations of key terminology and methods.

  •  Maintains Epidemiologic Rigor: Shows how molecular epidemiology builds upon traditional epidemiologic principles such as risk estimation, study design, and causal inference—enhancing rather than replacing them.

  •  Applications in Disease Prevention and Control: Demonstrates how molecular approaches can be used to identify at-risk populations, understand mechanisms of disease, and inform public health interventions.

  •  Groundbreaking and Influential: One of the first comprehensive resources in this emerging field, contributing to the formal development of molecular epidemiology as a distinct scientific discipline.

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