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Disordered Vertebral and Rib Morphology in Pudgy Mice: Structural Relationships to Human Congenital Scoliosis

Disordered Vertebral and Rib Morphology in Pudgy Mice: Structural Relationships to Human Congenital Scoliosis

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ISBN

978-3319431499

Authors

Frederic Shapiro

Edition Number

1st

Copyright Year

September 30, 2016

File Size

50 MB

Publisher

Springer

Pages

132

Vertebral and Rib Development in Pudgy Mice: Insights into Congenital Scoliosis

Vertebral and Rib Development in Pudgy Mice: Insights into Congenital Scoliosis explores the structural abnormalities of the vertebral column and ribs in pudgy mice as a model for understanding human congenital scoliosis. Combining radiological, histological, and developmental analyses, the book examines how genetic mutations influence spinal development and the resulting skeletal deformities. It provides valuable insights into vertebral embryology, pathology, and comparative anatomy for researchers and clinicians.

Key Features

  • Examines vertebral and rib abnormalities in a mouse model of congenital scoliosis.
  • Presents detailed radiological, histological, and whole-mount anatomical studies.
  • Explores the effects of Dll3 gene mutations on vertebral development.
  • Compares vertebral development in mice, chicks, and humans.
  • Discusses spinal cord, nerve roots, intervertebral discs, and associated skeletal structures.
  • Provides insights into the developmental mechanisms underlying congenital spinal deformities.
  • Ideal for researchers, veterinary anatomists, developmental biologists, and orthopedic specialists.
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