Charney & Nestler's Neurobiology of Mental Illness

This authoritative textbook provides a comprehensive understanding of the biological basis of mental illnesses. It bridges laboratory research with clinical applications, offering insights into the molecular, cellular, and systems-level mechanisms underlying psychiatric disorders. The fifth edition has been updated to include recent scientific advancements and to address ongoing debates in psychiatric diagnosis.

Key Features:

• Comprehensive Coverage: Discusses the neurobiology and genetics of major psychiatric disorders, including psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and childhood-onset disorders.
• Methodological Advances: Highlights recent developments in complex genetics, epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. 
• Diagnostic Perspectives: Examines traditional diagnostic approaches (DSM-5) alongside the Research Domain Criteria (RDoC) framework, exploring their implications for future psychiatric classification.
• Clinical Relevance: Provides insights into current therapeutic approaches and discusses how research advances are guiding the search for new treatments.
• Expert Contributions: Features chapters authored by leading experts in the field, ensuring authoritative and up-to-date information.