Cell-Based Assays Using iPSCs for Drug Development and Testing

Master Cell-Based Assays with iPSCs

This book provides a variety of protocols useful for researchers in disease modeling, drug discovery, and cell biology. It's a valuable resource for those working with human induced pluripotent cell lines (iPSCs) for drug development and testing.

Key Features

• iPSC Protocols: Covers requirements for using iPSCs, culture methods using bioreactor technologies, and specific protocols for iPSC-derived cardiomyocytes.
• Tissue-Specific Distinctions: Details the distinctions between various cell types, including hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons.
• High-Content Assays: Explores high-content assays for mitochondrial function and autophagy.
• Practical Guidance: Written in the highly successful Methods in Molecular Biology series format, chapters include step-by-step, readily reproducible laboratory protocols and tips for troubleshooting.
• Cutting-Edge Research: A valuable resource for researchers looking to learn more about this important and developing field.