An Introduction to Toxicology

 An Introduction to Toxicology

An Introduction to Toxicology by Philip C. Burcham provides an accessible overview of modern toxicology, focusing on how foreign chemicals interact with biological systems and cause harmful effects. It explains the mechanisms of toxicity, including the conversion of chemicals into reactive metabolites, cellular damage, and changes to DNA and proteins. With particular attention to cancer, birth defects, and organ injury, the book introduces key concepts relevant to medicines, environmental pollutants, and industrial chemicals. It is suitable for undergraduate and graduate students studying toxicology, pharmacology, and biomedical sciences.

Key Features

• Introduces the fundamental principles and concepts of modern toxicology.
• Explains how foreign chemicals interact with biological systems.
• Explores bioactivation and the formation of toxic metabolites.
• Examines the mechanisms responsible for chemical-induced cellular injury.
• Discusses damage to cellular DNA and proteins.
• Explains how toxic exposures may contribute to cancer and birth defects.
• Covers mechanisms of organ injury caused by harmful substances.
• Relates toxicological principles to health effects associated with alcohol and tobacco.
• Addresses the toxicological effects of medicines, environmental pollutants, and industrial chemicals.
• Uses illustrations and accessible explanations to support learning in toxicology and pharmacology.